@article{Reza2023,

title = {Short Note on Asteraceae as Traditional Food and Medicinal Plants in Cihanjawar Village, Purwakarta Regency, West Java},

author = {Reza Raihandhany, Angga Dwiartama, Rina Ratnasih},

doi = {http://journals.itb.ac.id/index.php/3bio},

issn = {2655-8777},

year  = {2023},

date = {2023-11-20},

urldate = {2023-11-20},

journal = {Journal of Biological Science, Technology and Management },

volume = {5},

issue = {1},

pages = {62-167},

abstract = {Asteraceae is known as the largest family of flowering plants. Despite some species members being invasive plants, these species are often adopted and utilized by local community groups for food, traditional medicine, and other uses. In our ethno- botanical study of Asteraceae, we identified ways a local Sundanese community group in West Java utilizes a diverse range of species in the family for different purposes. Our study focuses on a Sundanese village called Cihanjawar, located in the regency of Purwakarta, using ethnobotany and ethnomedicine approaches. People of Cihanjawar utilize some species of Asteraceae for food as ‘lalapan’ and traditional medicinal purposes. In-depth, semi-structured interviews with the people of Cihanjawar were conducted to collect primary data regarding the utilization of Asteraceae species as food and traditional medicine. A total of eight species of Asteraceae were found during the field-guided exploration in Cihanjawar Village, which include Acmella paniculata, Ageratum conyzoides, Calyptocarpus vialis, Crassocephalum crepidioides, Dichrocepala integrifolia, Emilia son- chifolia, Erechtites valerianifolia, Sphagneticola trilobata, some of which are considered invasive alien species. The species of A. paniculata, C. crepidioides, E. sonchifolia, Er. valerianifolia is eaten as a raw food (lalapan, Ind.). Then Ag. Conyzoides and C. crepidioides are utilized in traditional medicine. C. vialis, D. integrifolia, and Sphagneticola trilobata are not used by the people of Cihanjawar as food or as traditional medicine.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Vu2022,

title = {Soil Mineral Composition and Salinity Are the Main Factors Regulating the Bacterial Community Associated with the Roots of Coastal Sand Dune Halophytes},

author = {Minh Thiet Vu and Almando Geraldi and Hoang Dang Khoa Do and Arif Luqman and Hoang Danh Nguyen and Faiza Nur Fauzia and Fahmi Ikhlasul Amalludin and Aliffa Yusti Sadila and Nabilla Hapsari Wijaya and Heri Santoso and Yosephine Sri Wulan Manuhara and Le Minh Bui and Sucipto Hariyanto and Anjar Tri Wibowo},

editor = {Christian Staehelin and James White},

url = {https://doi.org/10.3390/biology11050695},

doi = {https://doi.org/10.3390/biology11050695},

year  = {2022},

date = {2022-04-30},

journal = {Biology},

volume = {11},

number = {695},

pages = {1-14},

abstract = {Soil salinity and mineral deficiency are major problems in agriculture. Many studies have reported that plant-associated microbiota, particularly rhizosphere and root microbiota, play a crucial role in tolerance against salinity and mineral deficiency. Nevertheless, there are still many unknown parts of plant\textendashmicrobe interaction, especially regarding their role in halophyte adaptation to coastal ecosystems. Here, we report the bacterial community associated with the roots of coastal sand dune halophytes Spinifex littoreus and Calotropis gigantea, and the soil properties that affect their composition. Strong correlations were observed between root bacterial diversity and soil mineral composition, especially with soil Calcium (Ca), Titanium (Ti), Cuprum (Cu), and Zinc (Zn) content. Soil Ti and Zn content showed a positive correlation with bacterial diversity, while soil Ca and Cu had a negative effect on bacterial diversity. A strong correlation was also found between the abundance of several bacterial species with soil salinity and mineral content, suggesting that some bacteria are responsive to changes in soil salinity and mineral content. Some of the identified bacteria, such as Bacillus idriensis and Kibdelosporangium aridum, are known to have growth-promoting effects on plants. Together, the findings of this work provided valuable information regarding bacterial communities associated with the roots of sand dune halophytes and their interactions with soil properties. Furthermore, we also identified several bacterial species that might be involved in tolerance against stresses. Further work will be focused on isolation and transplantation of these potential microbes, to validate their role in plant tolerance against stresses, not only in their native hosts but also in crops.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bidiarti2022,

title = {KAJIAN ETNOKULINER TRADISIONAL LINGGA SEBAGAI PENOPANG PENGEMBANGAN PARIWISATA},

author = {Risna Bidiarti and Syafroni Pranata and Fitmawati},

url = {http://publikasikr.lipi.go.id/index.php/buletin/article/view/780},

doi = {https://doi.org/10.14203/bkr.v25i1.780},

year  = {2022},

date = {2022-04-30},

journal = {Buletin Kebun Raya},

volume = {25},

number = {1},

pages = {44-56},

abstract = {Masakan tradisional Lingga merupakan masakan khas melayu nusantara yang masih dipertahankan sampai sekarang, dan identik dengan wisata Lingga. Penelitian ini bertujuan untuk mengetahui jenis tumbuhan dan pemanfaatan lokalnya pada etnokuliner Lingga, dan didukung dengan analisis metabolit sekunder sebagai penunjang pengembangan wisata Lingga. Penelitian ini dilakukan pada Oktober 2019 hingga Februari 2020. Pengumpulan data dilakukan dengan wawancara kepada informan. Selanjutnya dilakukan identifikasi, pengujian senyawa metabolit sekunder, dan analisis data. Hasil penelitian didapatkan 35 varian makanan tradisional Lingga yang menggunakan tumbuhan sebagai bahan utama dalam masakan yaitu 16 famili dan 31 jenis. Makanan tersebut terdiri atas tiga kelompok yang terbagi menjadi tujuh makanan yaitu kue kering, kue basah, makanan pokok, lauk pauk, sayur mayur, dan makanan khas hari besar Islam. Masakan tradisional Lingga ini banyak menggunakan bagian tumbuhan seperti daun, batang, dan umbi. Famili tumbuhan yang sering digunakan dalam masakan tradisional Lingga adalah Arecaceae, Lamiaceae, Euphorbiaceae, dan Zingiberaceae. Famili tersebut memiliki khasiat obat dan digunakan dalam pengobatan tradisional oleh masyarakat Lingga. Hasil uji metabolit sekunder menunjukkan adanya kandungan senyawa alkaloid, flavonoid, saponin, steroid, terpenoid, dan tanin di dalam tumbuhan yang digunakan dalam masakan.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Rizqi2022,

title = {Growth of Kaffir Lime (Citrus hystrix DC) Cell Line Derived from Seed Explant After Yeast Elicitation Using Pure and Technical Grade Yeast},

author = {Dewi Yuliana Rizqi and Frisca Damayanti and Ghea Putri Cristy and Alisa Julia Nurulita and Aries Bagus and Sasongko and Endang Semiarti and Woro Anindito Sri Tunjung},

url = {https://jurnal.ugm.ac.id/jtbb/article/view/68650},

doi = {https://doi.org/10.22146/jtbb.68650},

issn = {2540-9581},

year  = {2022},

date = {2022-03-22},

journal = {J. Tropical Biodiversity Biotechnology},

volume = {7},

number = {1},

pages = {1-14},

abstract = {The addition of elicitors in kaffir lime (Citrus hystrix DC.) culture is one of strategies for obtaining and increasing the production of secondary metabolites. Saccharomyces cerevisiae is one of the elicitors that can be used to increase secondary metabolites such as terpenoids. However, in its use, the pure cultures of S. cerevisiae are expensive. Therefore, the first objective of this study was to analyze the ability of technical grade (commercial baker’s yeast) to be used as an elicitor and measure the growth of kaffir lime cell line after being elicited by pure and technical grade (commercial baker’s yeast). The second objective is to determine the best time to subculture kaffir lime cell line after elicitation. We observed the morphology and measured the growth curve of pure and technical grade yeast until the 4th subculture generation. Furthermore, we used both grades of yeast for elicitation. Kaffir lime cell suspension was treated with 10 ppm pure grade or 5 ppm and 10 ppm technical grade yeast for 4 days. After elicitation, kaffir lime cell lines were subcultured and their growth was analyzed. The result showed that the morphology and growth curve of technical grade until 4th subculture generations was similar to the pure grade. On the other hand, after elicitation using pure and technical grade yeast and being subcultured, the growth of the elicitated kaffir lime cell line had the same pattern as the control group, but the cell density of the control group was higher than the elicitated group. The initial stationary phase of kaffir lime cell line was on the 17th day which is the best time to subculture. The subculturing process is important to maintain the viability of the kaffir lime cell line.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Dibha2022,

title = {Biological activity of kencur (Kaempferia galanga L.) against SARS-CoV-2 main protease},

author = {Alyaa Farrah Dibha and Sri Wahyuningsih and Viol Dhea Kharisma and Arif Nur Muhammad Ansori and Muhammad Hermawan Widyananda and Arli Aditya Parikesit and Maksim Rebezov and Yulia Matrosova and Svetlana Artyukhova and Nadezhda Kenijz and Maria Kiseleva and Vikash Jakhmola and Rahadian Zainul},

url = {https://sciencescholar.us/journal/index.php/ijhs/article/view/4779},

doi = {https://doi.org/10.53730/ijhs.v6nS1.4779},

year  = {2022},

date = {2022-03-15},

journal = {International Journal of Health Sciences},

volume = {6},

number = {S1},

pages = {468\textendash480},

abstract = {COVID-19 is a syndrome affecting pulmonary function but rather in serious conditions leads to death. Kencur (Kaempferia galanga L.) is a type of rhizome plant in Indonesia that is used as an herbal medicine called Jamu because it is believed to be able to cure various types of diseases. One of which is for anti-virus. The goal of this study was to see how effective the compounds in kencur are against COVID-19 with a molecular docking strategy. Kencur biological activities were obtained from the library and the design of the Acute Respiratory Syndrome Main protease (Mpro) has been gained from the protein data bank website. In addition, the biological activities in kencur were examined utilizing Lipinski's five-point concept was used to evaluate their substance molecular characteristics. Molecular docking analysis was performed with the PyRx Virtual Screening Tool software. The PyRx program was used for molecular docking simulation. While, the Discovery Studio Visualizer program was used to visualize the interaction between SARS-CoV-2 (Mpro) and the pharmacologically active metabolites in kencur. The docking evaluation on three antiviral substances revealed that Quercetin had the lowest binding energy when bound with Mpro and thus had the greatest potential as a viral inhibitor.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sofiyanti2022,

title = {Baccaurea Lour. (Phyllanthaceae Martinov-Malpighiales), underutilized plant from Riau, Indonesia and its phytochemical study},

author = {NERY SOFIYANTI and FITMAWATI and MAYTA NOVALIZA ISDA and ASIH RAHAYU AJENG AGESTI and MAYA SARI and Syafroni Pranata },

url = {https://smujo.id/biodiv/article/view/9696},

doi = {DOI: 10.13057/biodiv/d230236},

issn = {2085-4722},

year  = {2022},

date = {2022-02-28},

journal = {Biodiversitas},

volume = {23},

number = {2},

pages = { 937-946},

abstract = {Baccaurea Lour. (Phyllanthaceae Martinov-Malpighiales), underutilized plant from Riau, Indonesia and its phytochemical study. Biodiversitas 23: 937-946. Baccaurea (Phyllantaceae) is one of underutilized plants in Riau Province, Indonesia. Our finding in some districts shows the variation of morphological characters of Baccaurea members. However, there is no detailed morphological study of these genera reported from this province. This study aimed to identify Baccaurea species from Riau and characterized their morphology, as well as, phytochemical contents. The specimens were collected from the field, documented and observed in detail their morphological characters. Phytochemical screening had been conducted using qualitative tests of a total of six secondary metabolites (alkaloid, terpenoid, steroid, tannin, flavonoid and saponin). A total of seven Baccaurea species were identified in this study. The main characteristic that can be used to distinguish each species are leaf characteristics (venation, size and shape), floral pattern and fruit characters. The phytochemical contents vary among the examined Baccaurea. Steroid and tannin are absent from all of examined specimens. Terpenoid is commonly found in all fruit parts of all specimens.  The result of this study provides the first detailed morphological record as well as phytochemical data of Baccaurea from Riau.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hidayat2022,

title = {The Morphologies of Mudskipper Pelvic Fins in Relation to Terrestrial and Climbing Behaviour},

author = {Saifullah Hidayat and Adhityo Wicaksono and Anita Raharjeng and Desmond Soo Mun Jin and Parvez Alam and Bambang Retnoaji a},

url = {https://link.springer.com/article/10.1007/s12595-021-00422-1#citeas},

doi = {https://doi.org/10.1007/s12595-021-00422-1},

year  = {2022},

date = {2022-02-22},

journal = {Proceedings of the Zoological Society},

volume = {75},

pages = {83\textendash93},

abstract = {Two species of mudskipper are identified with different behaviours, which are related to their pelvic fin morphologies. Periophthalmus variabilis has unfused pelvic fins and is capable to climb on the vertical substrate. Another species, Boleophthalmus boddarti has fused pelvic fins which supports the fish mobility across the muddy substrate. In context of anatomy, both pelvic fins are composed of a frenum which covers the pelvic girdle and pelvic fin rays (lepidotrichia). The unfused pelvic fin of P. variabilis has split rays that are not interconnected, whereas the pelvic fins of B. boddarti are fused completely and the fin rays are merged to the skin. The pelvic fin ray bones of B. boddarti are composed of large bone structure, allowing it to function as a strong sitting pad on a semi-terrestrial substrate. Comparatively, in P. variabilis, the ray bones are shorter, hence provides flexibility to grip more surface area for the fish to stick during vertical locomotion. Histologically, the epidermal layer of B. boddarti pelvic fins has lower quantities of mucous cell than in P. variabilis, by 14.33 ± 1.53 and 33.33 ± 1.53 mucous cells per 100 epithelial cells, respectively. This difference reveals that more mucus is produced in P. variabilis, hence possibly giving this fish an enhanced capacity for Stefan adhesion on a terrestrial substrate than in B. boddarti. From this, the terrestrial locomotion and climbing ability are more supported in P. variabilis, compared to the more aquatic B. boddarti.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kharisma2022,

title = {Herbal combination from Moringa oleifera Lam. and Curcuma longa L. as SARS-CoV-2 antiviral via dual inhibitor pathway: A viroinformatics approach},

author = {Viol Dhea Kharisma and Aggy Agatha and Arif Nur Muhammad Ansori and Muhammad Hermawan Widyananda and Wahyu Choirur Rizky and Tim Godefridus Antonius Dings and Marina Derkho and Irina Lykasova and Yulanda Antonius and Imam Rosadi and Rahadian Zainul},

url = {https://jppres.com/jppres/moringa-oleifera-and-curcuma-longa-versus-sars-cov-2/},

year  = {2022},

date = {2022-02-01},

journal = {J Pharm Pharmacogn Res},

volume = {10},

number = {1},

pages = {138-146},

abstract = {Context: The COVID-19 outbreak is caused by the transmission and infection of SARS-CoV-2 at the end of 2019. It has led many countries to implement lockdown policies to prevent the viral spreading. Problems arise in a COVID-19 patient because of viral infection that leads to a systemic response in the immune system, specifically due to cytokine storm. Moreover, the antiviral drugs that have not been found. Indonesia had a variety of traditional medicines, such as is ‘jamu’. It consists of a mixture of natural ingredients such as Moringa oleifera Lam. and Curcuma longa L.



Aims: To identify the activity of dual inhibitors as antiviral and anti-inflammatory agents from herbal combination compounds.



Methods: Sample was collected from PubChem (NCBI, USA) and Protein Data Bank (PDB), then drug-likeness analysis using Lipinski rule of five in SCFBIO web server and bioactive probability analysis of bioactive compounds were conducted by PASS web server. Furthermore, the blind docking method was performed using PyRx 0.8 software to determine the binding activity and molecular interaction by PoseView web server and PyMol software v2.4.1 (Schr\"{o}dinger, Inc, USA).



Results: Cryptochlorogenic acid and curcumin have been computationally proven as dual inhibitors for antivirals by inhibiting Mpro SARS-CoV-2 and as anti-inflammatory through inhibition of NFKB1 activity. However, the results are merely computational so that it must be validated through a wet lab research.



Conclusions: The combination of Moringa oleifera Lam. and Curcuma longa L. is predicted to have antiviral and anti-inflammatory activity through dual inhibitor mechanism played by cryptochlorogenic acid and curcumin.



Keywords: COVID-19; Curcuma longa; Moringa oleifera; Mpro; NFKB1.



},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wibowo2021,

title = {Microplastic Contamination in the Human Gastrointestinal Tract and Daily Consumables Associated with an Indonesian Farming Community},

author = {Anjar Tri Wibowo and Husna Nugrahapraja and Ruri Agung Wahyuono and Izzatul Islami and Muhammad Husain Haekal and Yasri Fardiansyah and Pramudya Wisnu Wicaksono Sugiyo and Yohanes Kartjito Putro and Faiza Nur Fauzia and Heri Santoso and Friedrich G\"{o}tz and Bieby Voijant Tangahu and Arif Luqman},

doi = {https://doi.org/10.3390/su132212840},

year  = {2021},

date = {2021-11-19},

journal = {Sustainability},

volume = {13},

number = {12840},

pages = {1-10},

abstract = {Plastic is one of the most abundant pollutants in the environment. As a result of natural physical processes, large plastic waste is degraded into microsized particles (\<5 mm) called microplastics. Because of their size, abundance, and durability, microplastics are widely distributed in the environment, contaminating food and water intended for human consumption. The extent of microplastic contamination in the human body is still unclear because there are few studies concerning microplastic contamination in human specimens and, in most studies, data were collected from city dwellers. Despite having the fourth largest population and being the fourth largest plastic waste producer in the world and second largest plastic polluter in the ocean, there are currently no data with respect to microplastic exposure for the Indonesian population. Several studies have reported on microplastic contamination in seafood and freshwater organisms from Indonesia, and it is likely that microplastics have contaminated the gastrointestinal tracts of Indonesians. Using Raman spectroscopy, we detected microplastic contamination in 7 out of 11 analyzed stool samples collected from a farming community in the highland village of Pacet, East Java, Indonesia. Polypropylene (PP) was the most abundant and prevalent type of microplastic observed, and it was found in four of the positive samples with an average concentration of 10.19 microgram per gram of feces (µg/g). Microplastics were also detected at high concentrations in tempeh (soybean cake, a staple protein source for Indonesians), table salts, and toothpaste, which were regularly consumed and used by the study participants. PP was particularly high in table salts (2.6 µg/g) and toothpaste (15.42 µg/g), suggesting that these products might contribute to the gastrointestinal contamination in the studied population. This pilot study indicated microplastic contamination in the rural Indonesian population and in their daily consumables, demonstrating the far-reaching extent of microplastic pollution beyond urban areas.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kharisma2021,

title = {Concept of SARS-CoV-2 Vaccine Design to Fight COVID-19 Pandemic: A Review Insight},

author = {Viol Dhea Kharisma and Arif Nur Muhammad Ansori and Rasyadan Taufiq Probojati and Dora Dayu Rahma Turista and Yulanda Antonius},

doi = {10.37506/ijfmt.v15i4.17127},

year  = {2021},

date = {2021-11-17},

journal = {Indian Journal of Forensic Medicine \& Toxicology},

volume = {15},

number = {4},

pages = {2797-2803},

abstract = {Cluster of pneumonia infection emerged in Wuhan, China due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Additionally, more than 190 countries have confirmed 82 million cases of SARS-CoV-2 infection. Currently, there is a SARS-CoV-2 epidemic, and no effective prophylactic methods are available. A vaccine is considered as an effective method to restrict an epidemic. Several vaccine designing techniques have been established, which is enabling researchers from various institutes for developing vaccine towards SARS-CoV-2 infections. In this review, we condense the development of vaccine research against SARS-CoV-2.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ansori2021ab,

title = {Severe Acute Respiratory Syndrome Coronavirus-2 Emergence and Its Treatment with Alternative Medicines: A Review},

author = {Arif NM Ansori and Viol Dhea Kharisma and Amaq Fadholly and Martia Tacharina and Yulanda Antonius and Arli Aditya Parikesit },

doi = {http://dx.doi.org/10.52711/0974-360X.2021.00967},

year  = {2021},

date = {2021-10-06},

journal = {Research Journal of Pharmacy and Technology},

pages = {5551-5557},

abstract = {Known as the causal factor of the recent global COVID-19 pandemic, any SARS-CoV-2 is not the only coronavirus that has constituted a menace to society and taken thousands of human lives. Two previous pandemics were also led by coronaviruses; such as the MERS-CoV in 2012 and another SARS-CoV in 2002. Only five months into existence, SARS-CoV-2 transmitted infection to approximately 75 million people and it has led to more than 1.5 million of deaths all over the world. Unfortunately, there has not been any specific treatment yet for COVID-19 yet and its control is purely empirical. The examinations of the parity between SARS-CoV-2 and SARS-CoV, in terms of their genomics, origin, epidemiology, and pathogenesis, suggested that we may use the previous data of MERS-CoV or SARS-CoV as a guideline for uncovering the effective approach to strive against SARS-CoV-2. Various studies have reported the positive effects of numerous phytochemical compounds against SARS-CoV and MERS-CoV. Interestingly, this idea has been emplyed for SARS-CoV-2, and in silico screening of phytochemical compounds has been performed for identifying the potential candidates for COVID-19 treatment. Curcumin is an example of a natural compound which was demonstrated as potent candidate contrary to SARS-CoV-2 protease derived from the in silico studies. Herein, the occurrence of SARS-CoV-2 and the aplication of alternative medicines for treating coronavirus diseases are briefly reviewed.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wijaya2021,

title = {COVID-19 In Silico Drug with Zingiber officinale Natural Product Compound Library Targeting the Mpro Protein},

author = {Renadya Maulani Wijaya and Muhammad Aldino Hafidzhah and Viol Dhea Kharisma and Arif Nur Muhammad Ansori and Arli Aditya Parikesit},

url = {https://scholarhub.ui.ac.id/science/vol25/iss3/5?utm_source=scholarhub.ui.ac.id%2Fscience%2Fvol25%2Fiss3%2F5\&utm_medium=PDF\&utm_campaign=PDFCoverPages},

doi = {https://doi.org/10.7454/mss.v25i3.1244},

year  = {2021},

date = {2021-09-30},

journal = {Makara Journal of Science},

volume = {25},

number = {3},

pages = {162-171},

abstract = {Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a worldwide pandemic. Ginger (Zingiber officinale) is a rhizome, which is commonly used for culinary and medicinal purposes. In Indonesia, ginger is taken as traditional medicine by processing it into a drink known as jamu. The present study aimed to assess and evaluate the bioactive compounds in ginger that can be used in drug design for treating COVID-19. The crystal structure of the SARS-CoV-2 main protease (Mpro) was generated from a protein sequence database, i.e., Protein Data Bank, and the bioactive compounds in ginger were derived from the existing compounds library. Mpro is involved in polyprotein synthesis, including viral maturation and nonstructural protein gluing, making it a potential antiviral target. Furthermore, the bioactive compounds in ginger were analyzed using Lipinski’s rule of five to determine their drug-like molecular properties. Moreover, molecular docking analysis was conducted using the Python Prescription 0.8 (Virtual Screening Tool) software, and the interaction between SARS-CoV-2 Mpro and the bioactive compounds in ginger was extensively examined using the PyMOL software. Out all of the 16 bioactive compounds that were docked successfully, 4-gingerol, which has the lowest binding energy against SARS-CoV-2 Mpro, as per the virtual screening results, was proven to have the most potential as a viral inhibitor of SARS-CoV-2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wicaksono2021ab,

title = {Kopyor versus macapuno coconuts: are these two edible mutants of Southeast Asia the same?},

author = {Adhityo Wicaksono and Reza Raihandhany and Jaime A. Teixeira da Silva },

url = {https://link.springer.com/article/10.1007/s00425-021-03740-y#citeas},

doi = {https://doi.org/10.1007/s00425-021-03740-y},

year  = {2021},

date = {2021-09-28},

journal = {Planta},

volume = {254},

number = {86},

abstract = {Coconut (Cocos nucifera L.; Arecaceae), a widely distributed plant with popular culinary applications, especially of the endosperm, has several nutritional and medicinal benefits. Two coconut mutants are widely recognized in Southeast Asia, namely kopyor and macapuno, specifically in Indonesia and Philippines, respectively. Kopyor coconut is known for its brittle solid endosperm while macapuno coconut is known for its gelatinous solid endosperm. Both mutant types have many other synonyms in other countries. Over many decades, the biology of macapuno coconut, including endosperm anatomy, histology, cytology, physiology, and genetics have been described, while kopyor coconut is still understudied. However, some literature and websites erroneously describe kopyor as macapuno coconut, or consider them interchangeably, which is an unintentional consequence of insufficient scientific research on these coconut mutants. Additionally, in Indonesia, there is another local mutant in Banten called wax coconut (“kelapa lilin”) that some researchers claim as the actual Indonesian macapuno coconut due to its strong resemblance to kopyor coconut. Unfortunately, wax coconut is not only understudied, it is rarely documented. Additional evidence of their differences, in terms of morphological, biochemical and genetic characteristics, is needed. Moreover, clear documentation will also be needed for a better comparison. Understanding the differences between kopyor and macapuno coconuts will not only help to further clarify their scientific description in the literature, but will also guide locals, researchers, and industries to characterize similar mutants, if found in specific regions, for future study and bioprospecting.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hasan2021,

title = {Two new localities for Lobocheilos falcifer (Valenciennes, 1842) (Teleostei: Cyprinidae), a rare and vulnerable freshwater fish species of Java, Indonesia},

author = {Veryl Hasan and Lucas de Oliveira Vieira and Felipe Polivanov Ottoni and Endang Dewi Masithah},

url = {https://doi.org/10.22034/ijab.v9i4.1285},

doi = {https://doi.org/10.22034/ijab.v9i4.1285},

issn = {2322-5270},

year  = {2021},

date = {2021-08-25},

journal = {Int. J. Aquat. Biol.},

volume = {9},

number = {4},

pages = { 244-247},

abstract = {Lobocheilos falcifer is a rare and vulnerable freshwater fish species from Java, Indonesia and currently listed as Vulnerable (VU) within the IUCN Red List. In 2019, three specimens of L. falcifer were collected and photographed on Rawa Pening Lake, Semarang Regency, Central Java Province and Solo River, Karanganyar Regency, Central Java Province as two new localities for this species, extending its distribution in about 80 km to southeast. We also provided the morphological data of this species as well.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Nurtjahyani2021,

title = {Haplotype Network Analysis and Phylogenetic Tree Construction of Hepatitis C Virus (HCV) Isolated from Tuban, Indonesia},

author = {Supiana Dian Nurtjahyani and Rasyadan Taufiq Probojati and Arif Nur Muhammad Ansori and Mochammad Amin and Retno Handajani},

url = {https://www.proquest.com/openview/108fa42e8fd99631652b05c590287236/1?pq-origsite=gscholar\&cbl=1096441},

doi = {10.52711/0974-360X.2021.00734},

issn = {0974-3618 },

year  = {2021},

date = {2021-08-12},

journal = {Research J. Pharm. and Tech. },

volume = {14},

number = {8},

pages = {4231-4235},

abstract = {This study aimed to analyzed the haplotype network and constructed the phylogenetic tree topology of hepatitis

C virus (HCV) in Tuban, Indonesia and those from other countries, to determine the visualize genealogical

relationship and inference about gene connected. The HCV isolates were collected from blood transfusion center

of Tuban, East Java, Indonesia in 2015 and as a comparison, also the sequences of HCV isolates were retrieved

from the GenBank®, National Center of Biotechnology Information (NCBI), USA database. To constructed of

distribution map was performed through median joining analysis using Haplotype Network v4.6, whereas to

constructed and phylogenetic model analyses were constructed based on the NS5B and 5’UTR regions using

MEGA X, maximum-likelihood method based on the Tamura-Nei model. In the HCV NS5B region haplotype

network showed high haplotype diversity (Hd=1.00) in 22 haplotypes. Based on phylogenetic analysis 3 sample

isolates Tuban (BDT-55-p23, BDT-79-p23 and BDT-112-p23) were identified one group and closely related to

isolates from Indonesia. However, isolates Tuban also have the same sequence characters as the isolates from

Thailand. It was also confirmed in haplotype network that the three isolates are connected to each other. The

identification of HCV genotypes circulating in blood donors in the Tuban of East Java confirmed were closely

related to HCV isolates from Indonesia and Thailand. Therefore, this result might contribute in a better medical

management towards HCV.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ansori2021e,

title = {Medicinal properties of Muntingia calabura L.: A Review},

author = {Arif Nur Muhammad Ansori and Viol Dhea Kharisma and Tridiganita Intan Solikhah},

doi = {10.52711/0974-360X.2021.00784},

issn = {0974-3618 },

year  = {2021},

date = {2021-08-12},

journal = {Research J. Pharm. and Tech. },

volume = {14},

number = {8},

pages = {4505-4508},

abstract = {Indonesia has abundant medicinal plants, which have been historically used by the population in treating

diseases for generations. Traditional Indonesian medicine and the medicinal plants used could lead to the

discovery of novel drugs. For example, Muntingia calabura L., also known as kersen, is a well-known medicinal

plant that has been used to treat various diseases worldwide. The pharmacological activities and phytochemical

composition of the whole plant of M. calabura L. have been investigated and identified by scientists in recent

decades. These studies have established the therapeutic potential of kersen for drug discovery. This present

review provides an overview of the ethnopharmacology, pharmacology, and phytochemistry of M. calabura L.

as they relate to its use against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Adhityo2021a,

title = {Upaya  Kultivasi  Jamur  Morel  (Morchella  esculenta  (L.)  Pers.) dari  Kawasan  Lembang,  Jawa  Barat  dan  Optimasi Pertumbuhannya dengan Menggunakan Media Pati},

author = {Adhityo Wicaksono and Reza Raihandhany and I Nyoman Pugeg Aryantha.},

url = {https://www.researchgate.net/publication/353598114_Upaya_Kultivasi_Jamur_Morel_Morchella_esculenta_L_Pers_dari_Kawasan_Lembang_Jawa_Barat_dan_Optimasi_Pertumbuhannya_dengan_Menggunakan_Media_Pati},

doi = {10.46638},

issn = {2579-8766},

year  = {2021},

date = {2021-07-31},

journal = {Jurnal Mikologi Indonesia},

volume = {5},

number = {1},

pages = {7-15},

abstract = {Jamur morel (Morchella esculenta (L.) Pers.) memiliki nilai gizi yang baik dan bernilai jual tinggi dari segi industri kuliner. Di Indonesia, jamur ini telah ditemukan di kawasan Gunung Rinjani, Nusa Tenggara Barat, dan di kawasan Lembang, Jawa Barat, yang menjadi spesimen dalam penelitian ini. Penelitian ini bertujuan untuk mencoba menginokulasi jamur morel pada media kultur murni, media bibit induk, dan media tanam. Kemudian pertumbuhan miselia dan laju tumbuhnyadiamati pada media karbohidrat yang dibuat dari tepung terigu, beras, maizena, dan tapioka pada cawan Petri. Kultur murni dengan menggunakan media agar dekstrosa kentang di cawan Petri telah membuahkan hasil, sebagaimana jamur morel telah membentuk miselia dan sklerotia pada media kultur. Hasil positif juga ditemukan pada tahap lanjutan, yaitu kultur bibit induk dengan media buah kapuk dan dedak. Akan tetapi, upaya kultur di baglog berisi media tanah kompos belum membuahkan hasil, sehinggaperlu diteliti lebih lanjut dan dilakukan optimasi. Pada percobaan optimasi media karbohidrat, miselia jamur morel tumbuh paling baik pada media tepung terigu, kemudian tepung beras, dan paling sedikit pada tepung maizena. Miselia tidak tumbuhpada media tepung tapioka. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kharisma2021a,

title = {MOLECULAR DOCKING AND DYNAMIC SIMULATION OF ENTRY INHIBITOR FROM TAMARINDUS INDICA BIOACTIVE COMPOUNDS AGAINST SARS-COV-2 INFECTION VIA VIROINFORMATICS STUDY},

author = {Viol Dhea Kharisma and Arif Nur Muhammad Ansori and Farida Aryani Dian and Wahyu Choirur Rizky and Tim Godefridus Antonius Dings and Rahadian Zainul and Alexander Patera Nugraha},

url = {https://connectjournals.com/03896.2021.21.3323},

issn = {0972-5075},

year  = {2021},

date = {2021-07-21},

journal = {Biochem. Cell. Arch.},

volume = {21},

number = {2},

pages = {3323-3327},

abstract = {A massive transmission of SARS-CoV-2, which happens particularly in developing countries has continuously triggered a COVID-19 tsunami and may genuinely increase the mortality number. The significant mortality rate caused by the SARS-CoV-2 pandemic has made it a major world problem. Viral infectivity could arise from the lack of information on the specific antiviral drug. Tamarindus indica has been proven to be a potential antiviral through in vivo research as it decreases viral load in animal viruses. Nevertheless, at the preliminary stage, evidence-based approach like in silico study is necessitated to evaluate its potential as an antiviral in humans. This study screened the content of the active compounds of Tamarindus indica and identified its potential as an antiviral toward SARS-CoV-2 through an entry inhibitor mechanism using bioinformatics tools. Sample retrieval was carried out in the database, then the sample was identified for drug-likeness on the server. Likewise, molecular docking and dynamic simulations were carried out on the identified bioactive compounds. The results showed that all the bioactive compounds possess drug-like molecules and β-sitosterol has the most negative binding affinity. Tamarindus indica is predicted to be an antiviral candidate for SARS-CoV-2 with an entry inhibitor mechanism through a compound, specifically called β-sitosterol.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Adhityo,

title = {Xenobiology: An expanded semantical review },

author = {Adhityo Wicaksono and Ghea Putri Cristy.},

url = {https://www.researchgate.net/publication/352712062_Xenobiology_An_expanded_semantical_review},

doi = {10.15835},

year  = {2021},

date = {2021-06-23},

journal = {Notulae Scientia Biologicae},

volume = {13},

number = {10929},

pages = {1-14},

abstract = {The definition of “xenobiology” has gradually shifted from the study of the foreign, estranged life forms 

potentially existing in outer space to the study where the natural and synthetic life are involved. The natural 

concept of xenobiology governs the unseen, hypothetical life on the outer space, and the hidden life with 

completely different biochemistry on Earth. The life on the outer space might possess different way to harvest 

energy from the one on Earth. The hidden life on Earth, or the “Shadow Biosphere” might rose from completely 

different way of creation and evolution on Earth, which lead to its complete difference from the known

biosphere. The newest concept of xenobiology involves synthetic life, built with unnatural base pair of the 

nucleic acid, with analogous or xeno nucleic acid (XNA), has a synthetic genome which capable of selfreplicating or enables the synthetic cell to self-replicate, or even possesses a synthetic physiological pathway. By 

understanding the broad spectrum of xenobiology, in both natural and synthetic concepts, we can expand our 

view on how life might develop into a completely estranged system, which is different from anthropocentric 

view of life available around us on Earth. From these perspectives, we might understand how life evolved by 

evolving it synthetically. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{wicaksono2021b,

title = {Promoter analysis of the SPATULA (FvSPT) and SPIRAL (FvSPR) genes in the woodland diploid strawberry (Fragaria vesca L.)},

author = {Norbert Hidv\'{e}gi and Andrea Guly\'{a}s and Teixeira da Silva, Jaime A and Adhityo Wicaksono and Erzs\'{e}bet Kiss },

url = {https://link.springer.com/article/10.1007%2Fs42977-021-00089-x},

doi = {https://doi.org/10.1007/s42977-021-00089-x},

issn = {2676-8607},

year  = {2021},

date = {2021-06-09},

journal = {Biologia Futura},

abstract = {The aim of this study was to identify transcription factor (TF) binding sites and cis-regulatory elements (CREs) on the

promoters of FvSPR1-like2 (SPIRAL) and FvSPT (SPATULA) genes in the woodland diploid strawberry (Fragaria vesca

L.). We identifed: (1) MYB59, WRKY25 and WRKY8 TFs which play a role in ethylene signaling; (2) ARF family of TFs

which play a role in ARF-mediated auxin signaling on the promoter of FvSPR1-like2 gene; (3) ARR family of TFs which

play a role in cytokinin signaling; (4) ERF family of TFs which play a role in ethylene signaling on the promoter of FvSPT.

This bioinformatic analysis of TFs and CREs may provide a better understanding of the function of genes involved in, and

the mechanism underlying, non-climateric ripening during strawberry fruit maturation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{wicaksono2021a,

title = {Rhizanthes, the Forgotten Relative of Rafflesia in the Rafflesiaceae},

author = {Adhityo Wicaksono and Ghea Putri Cristy and Reza Raihandhany and Sofi Mursidawati and Teixeira da Silva, Jaime A and Agus Susatya},

url = {https://link.springer.com/article/10.1007%2Fs12229-021-09261-3},

doi = {https://doi.org/10.1007/s12229-021-09261-3},

year  = {2021},

date = {2021-05-18},

journal = {The Botanical Review},

abstract = {Rhizanthes is a holoparasitic plant of the Rafflesiaceae, and, just like Rafflesia, its host

is Tetrastigma (Vitaceae). Unlike Rafflesia, very little research has been conducted on

Rhizanthes other than a few studies focusing on its taxonomy and anatomy, and limited

studies on its propagation, despite some ethnomedicinal uses in several regions of

Indonesia. Wild populations of Rhizanthes are declining due to deforestation and

overharvesting by locals. Artificial pollination and possible seed spread, which are

similar to Rafflesia, may be useful for future propagation-based studies, which are

generally very difficult and challenging for members of the Rafflesiaceae. This paper

emphasizes the cultural and ethnomedicinal importance of Rhizanthes and seeks to

define a conservation road-map that incorporates a scientifically-based approach to

research while also seeking a four-pronged approach to the conservation of Rhizanthes:

1) conventional and biotechnology-based conservation; 2) germplasm multiplication

and preservation; 3) reintroduction into the wild and conservation of wild populations;

4) policy-based protective measures.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wijayanti2021,

title = {Range expansion of Oreochromis niloticus (Linnaeys, 1758) (Perciformes, Chichlidae) in Java Sea and first record for Masalembo Island},

author = {A Wijayanti and Veryl Hasan and Muhammad Badrut Tamam},

url = {https://iopscience.iop.org/article/10.1088/1755-1315/718/1/012096/pdf},

doi = {10.1088/1755-1315/718/1/012096},

year  = {2021},

date = {2021-05-04},

journal = {IOP Conf. Series: Earth and Environmental Science },

volume = {718},

abstract = {Oreochromis niloticus (Linnaeus, 1758) is native to Africa, with introductions reported from Bawean Island and Kangean Island, Java Sea (Indonesia). In 2019, four specimens of O. niloticus were captured from an estuary (conservation area) on Masalembo Island. This record is among the first of this species from the middle of the Java Sea. A description of morphological characters of the specimens are provided.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Adhityo2021b,

title = {Tetrastigma leucostaphylum (Dennst.) Alston ex Mabb. Partial wedge sampling, a new, less-invasive solution for stem-borne versus root-borne Rafflesia identification},

author = {Sofi Mursidawati and Adhityo Wicaksono and Teixeira da Silva, Jaime A.},

url = {https://www.researchgate.net/publication/353356570_Tetrastigma_leucostaphylum_Dennst_Alston_ex_Mabb_Partial_wedge_sampling_a_new_less-invasive_solution_for_stem-borne_versus_root-borne_Rafflesia_identification},

issn = {0031-7683},

year  = {2021},

date = {2021-05-03},

journal = {Philippine Journal of Science},

volume = {150},

number = {5},

pages = {1141-1152},

abstract = {Tetrastigma (Vitaceae) are a genus of tropical lianas that are hosts for parasitic plants in the family Rafflesiaceae. Since the stem of Tetrastigma is creeping and often devoid of leaves, it is often mistakenly visually identified as a root. Rafflesia flowers at the ground level (i.e. terrestrial flowers) have been documented to grow on Tetrastigma roots, but it is unclear whether those that arise aerially emerge from host root or stem organs. In this study, we present a new, less-destructive means of sampling Tetrastigma leucostaphylum, which is a host of many Rafflesia species. Histological observation of two 250 cm above-ground aerial samples confirmed that both were stems, as shown by distinct anatomical features (compactly arranged vascular bundles with simple phloem bundles) in contrast to roots, which had loosely arranged vascular bundles with ramified phloem bundles. Clearer identification of Tetrastigma vine infected with aerial Rafflesia is needed to confirm whether the parasitic flower grows on a stem or on an erect aerial root to better understand the biology of this enigmatic Rafflesia species that have evaded cultivation and ex situ conservation efforts. This new sampling method may be a useful way to identify the Tetrastigma vine in the future due to its less invasive nature compared to severing the whole vine.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Effendi2021,

title = { Alstonia macrophylla (Apocynaceae): A New Record of Naturalized Species in Java, Indonesia. },

author = {Surianto Effendi and Wendy A. Mustaqim },

url = {https://www.ptti.or.id/journal/index.php/Floribunda/article/view/321},

doi = {10.32556/floribunda.v6i6.2021.321},

issn = {2460 - 6944},

year  = {2021},

date = {2021-04-30},

journal = {Floribunda},

volume = {6},

number = {6},

pages = {207-212},

abstract = {Alstonia macrophylla (Apocynaceae), a Malesian widespread species tree, here for the first time is formally reported to be naturally found in Java. The report is based on plants growing in the Ciampea limestone hills, Ciampea sub-district, west of Bogor, West Java. Description, ecology, illustration and a brief discussion regarding the occurrence state of this species as naturalized species in Java are presented. A key to Alstonia species in Java is also given.  },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ansori2021,

title = {Molecular docking study of sea urchin (Arbacia lixula) peptides as multi-target inhibitor for non-small cell lung cancer (NSCLC) associated proteins},

author = {Muhammad Hermawan Widyananda and Setyaki Kevin Pratama and Rizky Senna Samoedra and Fikriya Novita Sari and Viol Dhea Kharisma and Arif Nur Muhammad Ansori and Yulanda Antonius },

url = {https://jppres.wordpress.com/2021/05/04/molecular-docking-study-of-sea-urchin-arbacia-lixula-peptides-as-multi-target-inhibitor-for-non-small-cell-lung-cancer-nsclc-associated-proteins/},

issn = {0719-4250},

year  = {2021},

date = {2021-03-15},

journal = {Journal of Pharmacy \& Pharmacognosy Research},

volume = {9},

number = {4},

pages = {484-496},

abstract = {Context: Lung cancer is a type of cancer that causes the most deaths worldwide. The most common type of lung cancer is non-small cell lung cancer (NSCLC). Sea urchin (Arbacia lixula) has high potential as an anti-NSCLC agent.



Aims: To analyze the anticancer activity of peptides from A. lixula coelomic fluid in inhibiting the activity of NSCLC-related proteins.



Methods: Peptide modeling was performed using the PEP-FOLD3 web server. Proteins that have a crucial role in NSCLC progression were determined using KEGG pathway database. 3D protein structures such as EGFR, PI3K, BRAF V600E, and JAK3 were taken from the RCSB PDB database. Docking was performed using Autodock Vina software. Docking results analysis was carried out using Discovery Studio 2019 software.



Results: Some peptides bind to the active sites with low binding affinity. Peptide 10 binds to the active site of the EGFR with a binding affinity of -9 kcal/mol. Peptide 5 binds to the active sites of PI3K and BRAF V600E with binding affinity of -8.2 and -8.1 kcal/mol, respectively. Peptide 11 binds to the active site of JAK3 with a binding affinity of -8.1 kcal/mol. All of these peptides have lower binding affinity than ATP as the native ligand. Besides, these peptides also produce more hydrogen bonds than ATP, so they are predicted to be more stable.



Conclusions: Peptides 10, 5, and 11 have high potential as anti-NSCLC agents because they can inhibit the activity of proteins that play an essential role in the growth of NSCLC, namely EGFR, PI3K, BRAF V600E, and JAK3 through the competitive ATP inhibitor mechanism.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{wicaksono2021,

title = {The term “caline” in plant developmental biology},

author = {Adhityo Wicaksono and Judit Dobr\'{a}nszki and Jaime A. Teixeira da Silva},

url = {https://link.springer.com/article/10.1007%2Fs42977-021-00076-2},

doi = {https://doi.org/10.1007/s42977-021-00076-2},

year  = {2021},

date = {2021-03-01},

journal = {Biologia Futura},

abstract = {In the 1930s, Frits Warmolt Went conducted a number of seminal studies on pea seedlings that had been germinated in the

dark and assessed their growth when either the apical parts, cotyledons, or roots were cut of or grafted, to assess whether

coplant growth factors assisted auxin in the development of these organs. Went assigned the term “calines” to all auxinassisting substances, specifcally rhizocaline, caulocaline, and phyllocaline in root, shoot (and axillary buds) and leaf development, respectively. Those experiments were based exclusively on growth assays, and no supplementary biochemical or

physiological analyses were ever conducted, and additional proof was only provided by Went using pea or tomato. The lack

of independent reproducibility by other groups, combined with the fact that the hormonal control of these developmental

events in plants is now fairly well-studied event, even at the molecular level, suggests that these growth factors that Went

observed 80 years ago either do not exist or are known by some other term in modern plant development. The terms related

to “calines” should thus no longer be used in plant developmental biology.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ansori2021a,

title = {Tea catechin as antiviral agent via apoptosis agonist and triple inhibitor mechanism against HIV-1 infection: A bioinformatics approach},

author = {Viol Dhea Kharisma and Muhammad Hermawan Widyananda and Arif Nur Muhammad Ansori and Aondohemba Samuel

Nege and Sin War Naw and Alexander Patera Nugraha },

url = {https://jppres.com/jppres/in-silico-tea-catechin-as-hiv-antiretroviral-agent/},

issn = {0719-4250},

year  = {2021},

date = {2021-02-16},

journal = {Journal of Pharmacy \& Pharmacognosy Research},

volume = {9},

number = {4},

pages = {435-445},

abstract = {Context: Human immunodeficiency virus (HIV) antiretrovirals that

target the binding of viral enzyme are chosen as the lead solution in the

treatment of HIV-1 infection, such as non-catalytic site integrase

inhibitor (NCINI), nevirapine, and darunavir. There are natural

compounds from specific plants that can be effective in treating HIV-1

infection such as tea catechin. Tea catechin administration causes a

decrease in viral load and inhibition of entry mechanisms and an

increased effect of apoptosis in infected cells.

Aims: To identify the triple inhibitor mechanism in tea catechins against

the three HIV-1 enzymes and apoptosis agonists through in silico

approach as an innovation in handling HIV-1 infection.

Methods: The 3D structure of tea catechin compounds from the database

was examined, and then all target compounds were analyzed for druglikeness, molecular docking, pathway prediction, and molecular

interactions to determine the potential of tea catechin compounds as

antiviral HIV-1 in silico.

Results: Tea catechin compounds have the potential to serve as antiviral

against HIV-1 through apoptosis agonist and triple inhibitor

mechanisms. Apoptosis occurs due to the interaction of tea catechins

with pro-apoptotic proteins in cells, and the epigallocatechin gallate

(EGCG) compound is a class of tea catechins with the same binding

position as control.

Conclusions: The binding of the EGCG molecule complex results in low

binding energy. Therefore, it allows EGCG acts as a triple inhibitor in

HIV-1 infection.

},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Veryl2021,

title = {Presence of the vulnerable freshwater goby Sicyopus auxilimentus (Gobiidae, Sicydiinae) on Sangihe Island, Indonesia},

author = {Veryl Hasan and Fitri S. Valen and R. Adharyan Islamy and Maheno S. Widodo and Aditya Mirzapahlevi Saptadjaja and Izzul Islam},

url = {https://smujo.id/biodiv/article/view/7121},

doi = {10.13057/biodiv/d220208},

issn = {2085-4722 },

year  = {2021},

date = {2021-02-02},

journal = {Biodiversitas},

volume = {22},

number = {2},

pages = { 571-579},

abstract = {A single specimen of freshwater goby Sicyopus auxilimentus was photographed and collected using fish traps between 8 and 15 September 2019 in the Laine waterfall, Sangihe island district, North Sulawesi Province, Indonesia. S. auxilimentus is amphidromous that live in both freshwater and marine environments. This species is currently listed as Vulnerable (VU) within the IUCN Red List Status. The specimen was identified as male S. auxilimentus based on the coloration of the preserved specimen: background yellowish; scale edges brown; posterior flanks and caudal peduncle orange; first dorsal fin black, second dorsal fin dusky black; pectoral fin slightly brown; ventral fin slightly dusky; anal fin blackish; caudal fin dusky brown. Specific morphological features were as follows: the base of the first dorsal fin was not connected to the second dorsal fin base; distance between the base of first and second dorsal fin was generally less than half of eye diameter; ventral fin rays were fused to belly only between fifth rays; posterior margin of caudal fins rays was rounded; scales were all ctenoid; scales appeared on the caudal peduncle, and between anal and second dorsal fins; anterior to which, scales became widely spaced and did not imbricate. Meristic characters were as follows: first dorsal fin rays VI; second dorsal fin rays I+9; ventral fin rays I+5; pectoral-fin rays 14; anal-fin rays I+9; caudal-fin rays 13; scales in lateral series 13; scales in zigzag series 7; scales in transverse series backward 7; scales in transerves series forward 4. This finding is considered the first record in Sulawesi and the fifth from Indonesian waters after findings in Halmahera, Java, Bali and Lombok. This record enhances the understanding of the distribution of S. auxilimentus in Indonesian waters. Monitoring is needed to assess the possibility of Sangihe Island being a growth ground, spawning ground, and/or on the migration route of S. auxilimentus. In the Laine waterfall, Sangihe island, freshwater conditions were as follows: salinity 3.5 psu, temperature 23-25°C, and dissolved oxygen 7.7-9.2 mg/l, which were ideal habitat for S. auxilimentus. S. auxilimentus from Sangihe Island, had 0.000 genetic distance than from S. auxilimentus from Bali, while the next closest genetic distance was S. zosterophorus at genetic distance of 0.090. In addition to onsite conservation, domestication programs are needed to increase commercial availability without depending on natural catches.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Probojati2021,

title = {Phylogeny and estimated genetic divergence times of banana cultivars (Musa spp.) from Java Island by maturase K (matK) genes},

author = {Rasyadan Taufiq Probojati and Dwi Listyorini and Sulisetijono Sulisetijono and Didik Wahyudi},

url = {https://bnrc.springeropen.com/articles/10.1186/s42269-021-00492-3#citeas},

doi = {https://doi.org/10.1186/s42269-021-00492-3},

issn = {2522-8307},

year  = {2021},

date = {2021-02-01},

journal = {Bulletin of the National Research Centre},

volume = {45},

number = {33},

pages = {1-13},

abstract = {Background: The identifcation of banana cultivars genome is needed to provide a valid identity from the accession

of bananas which are used as basic data in the management of in situ and ex situ banana conservation as well as for

further breeding of banana cultivars.

Results: The size of PCR-amplifed matK ranged from 844 to 860 bp and showed a high variability. The haplotype

diversity was 0.9048 with nine haplotypes. Haplotype distribution map revealed the lineage patterns of banana

cultivars from Java. Reconstruction of genetic relationships using the maximum likelihood, maximum parsimony

and Bayesian inference algorithms produces tree topologies and classifcations that are grouped according to their

genomic groups, into three main clades, i.e., AA/AAA, AAB and ABB. Based on the previously derived age constraints

and fossil data, we estimate (Musaceae) that genetic divergence times of all samples occurred during the Eocene

(95% HPD: 51.9 Mya), Musa acuminata group (AA, AAA, AAB) with Musa balbisiana group (BB and ABB) occurred

during the Oligocene (95% HPD: 26 Mya), and the separation on each banana cultivars occurred during the Middle

Miocene to Pliocene (95% HPD: 16.5\textendash2.5 Mya).

Conclusions: From this study, we conclude that all studied cultivars are closely related according to its genomic

groups with high variation. Genetic variation among those cultivars creates nine haplotypes. The development of

variety which leads to the formation of diferent banana cultivars had suggested to be occurred long ago along with

human migration and domestication.

Keywords: Banana phylogeny, Banana divergence times, Banana genetic diversity, MatK gene, Banana in Java Island},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Viol2021a,

title = {Antiretroviral Effect Simulation from Black Tea (Camellia sinensis) via Dual Inhibitors Mechanism in HIV-1 and its Social Perspective in Indonesia},

author = {Viol Dhea Kharisma and Sasando Dhohan Kharisma and Arif Nur Muhammad Ansori and Hanny Priskila Kurniawan and Adiana Mutamsari Witaningrum and Amaq Fadholly and Martia Rani Tacharina},

url = {https://rjptonline.org/AbstractView.aspx?PID=2021-14-1-83},

doi = {10.5958/0974-360X.2021.00083.4},

issn = {0974-360X},

year  = {2021},

date = {2021-02-01},

journal = { Research Journal of Pharmacy and Technology},

volume = {14},

number = {1},

pages = {455-460},

abstract = {This study aims to investigate the general social perspective related to black tea (Camellia sinensis) as a traditional treatment in Indonesia, the potency of bioactive compounds in black tea as a dual inhibitor of the replication of HIV-1 as it inhibits the chemical interactions between ligands and target protein domain. The samples is prepared from specific databases that is about HIV-1 target protein, black tea chemical compounds, and HIV-1 drug compounds as positive control. After that the virtual screening, protein-ligand interaction, and molecular visualization tests were performed. Thirteen black tea compounds obtained from the database and 2 control compounds consisting of neverapine and darunavir. In addition, the 3D structure of the target protein from HIV-1 consisting of reverse transcriptase (RT) (ID 3LP1) and protease (PR) (ID 4HLA) was obtained from a protein database. Interestingly, the social perspective regarding HIV-1 treatment is predicted to be more likely to choose traditional medicine compared to the use of antiretroviral (ARV) drugs. Traditional medicine with black tea may be very popular among many people. In conclusion, almost all chemical compounds contained in black tea can inhibit the HIV-1 replication. Furthermore, there are two compounds that play an important role in the process because it is predicted to inhibit the biological activity of PR and RT in HIV-1, (-)-epicatechin-gallate and epigallocatechin-gallate called dual inhibitors.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Samitra2021,

title = {Amphibian Diversity in the Waterfall of Lubuklinggau City, South Sumatra},

author = {Dian Samitra and Zico Fakhrur Rozi},

url = {http://jurnal.radenfatah.ac.id/index.php/biota/article/view/6412},

doi = {https://doi.org/10.19109/Biota.v7i1.6412},

issn = {2460-7746},

year  = {2021},

date = {2021-01-23},

journal = {Biota},

volume = {7},

number = {1},

pages = {10-16},

abstract = {Temam and Sando Waterfalls are suitable habitats for amphibian life, the presence of tourist visits and additional facilities can cause disturbance to amphibians. However, amphibian data at the two locations have not been recorded. This study aims to determine diversity amphibians in the Temam and Sando Waterfall, Lubuklinggau City. The study was conducted from June to July 2020. The collection data used Visual Encounter Survey (VES) techniques and time search. The data were analyzed using relative abundance, and indexes of diversity, evenness, similarity, and dominance. 11 species of amphibians belonging to 5 families were found during the study. Odorrana hosii was found mostly during the study. Amphibian diversity in the waterfall of Temam and Sando Waterfall was categorized as low.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Viol2021,

title = {Revealing Potency of Bioactive Compounds as Inhibitor of Dengue Virus (DENV) NS2B/NS3 Protease from Sweet Potato (Ipomoea batatas L.) Leaves},

author = {Viol Dhea Kharisma and , Rasyadan Taufiq Probojati and Ahmad Affan Ali Murtadlo and Arif Nur Muhammad

Ansori and Yulanda Antonius and Muhammad Badrut Tamam },

url = {https://www.researchgate.net/profile/Viol_Kharisma/publication/348447925_Revealing_Potency_of_Bioactive_Compounds_as_Inhibitor_of_Dengue_Virus_DENV_NS2BNS3_Protease_from_Sweet_Potato_Ipomoea_batatas_L_Leaves/links/6000156ba6fdccdcb8518562/Revealing-Potency-of-Bioactive-Compounds-as-Inhibitor-of-Dengue-Virus-DENV-NS2B-NS3-Protease-from-Sweet-Potato-Ipomoea-batatas-L-Leaves.pdf},

doi = {10.37506/ijfmt.v15i1.13644},

issn = {0973-9130},

year  = {2021},

date = {2021-01-14},

journal = {Indian Journal of Forensic Medicine and Toxicology},

volume = {15},

number = {1},

pages = {1627-1632},

abstract = {This study aims to identify the potency of bioactive compounds of sweet potato leaf as inhibitory agent to dengue virus (DENV) NS2B/NS3 protease by using computational study. The 3D structure of NS2B/NS3 protease was collected from PDB and the 2D structure of several bioactive compounds of sweet potato leaf were obtained from PubChem. The visualization and data analysis were performed by using the PyMol software. According to the in silico analysis, result demonstrated that dehydroabietinol had the lowest free energy binding. However, based on the protein-ligand analysis, all the compounds showed the hydrogen bond and hydrophobic interaction. All the compounds with hydrogen bond could not be interacted with catalytic domain, but hydrophobic interaction could be interacted to the target domain via Ser135 by δ-Selinene and His51 by α-Caryophyllene. In summary, we conclude that δ-Selinene and α-Caryophyllene might have potencies as a therapeutically drug for dengue.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Serdiati2021,

title = {Range expansion of the Invasive Nile Tilapia Oreochromis niloticus (Perciformes: Cichlidae) in Sulawesi Sea and first record for Sangihe Island, Tahuna, North Sulawesi, Indonesia},

author = {Novalina Serdiati and LigaInsani and Muhammad Safir and Andi Heryanti Rukka and Septina F. Mangitung and Fitri Sil Valen Muhammad Badrut Tamam and Veryl Hasan},

url = {http://www.envirobiotechjournals.com/article_abstract.php?aid=11218\&iid=327\&jid=3},

year  = {2021},

date = {2021-01-01},

journal = {Eco. Env. \& Cons},

volume = {27},

number = {1},

pages = {168-171},

abstract = {Oreochromis niloticus (Linnaeus, 1758) is native species to North Africa, that has been introduced to many areas worldwide, including Indonesia. On 10-24 January 2020 specimens of O. niloticus were captured from Laine Waterfall in Sangihe Island, Indonesia, as a new record for this island. Introduced non-native fish would be able to have negative impacts on the aquatic species communities through competition food and other resources, so the existence of the O. niloticus is a risk. The characteristics of O. niloticus specimens were as follows dorsal spin rays 15, dorsal soft rays 11, pelvic spin rays 1, pelvic soft rays 5, pectoral fin rays 10, anal spin rays 8, anal soft rays 10. The specific morphological characters of a specimen are provided.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mustaqim2020mb,

title = {A new species of Syzygium (Myrtaceae) from the Bird’s Head Peninsula, western New Guinea},

author = {Wendy A. Mustaqim and Yee Wen Low and Charlie D. Heatubun },

doi = {dx.doi.org/10.7751/telopea14780},

issn = {2200-4025},

year  = {2020},

date = {2020-12-29},

journal = {Telopea Journal of Plant Systematics},

volume = {23},

pages = {221\textendash225},

abstract = {Syzygium oransbariense Mustaqim, Y.W.Low \& Heatubun (Myrtaceae) is here formally described. This species is found in the lowlands on the eastern flank of the Arfak Mountains, Bird’s Head Peninsula, western New Guinea. The species is similar to Syzygium longipes (Diels) Merr. \& L.M.Perry but differs based on a set of diagnostic morphological characters. Species description, distribution, a preliminary conservation status assessment, and notes on the new species are presented here.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Reza,

title = {Inventarisasi Keanekaragaman Spesies Tumbuhan Bawah di Kawasan Agrowisata Pangjugjugan, Desa Cilembu, Sumedang},

author = {Reza Raihandhany Yus and Dicky Nugraha and Rasyid Sidik

},

url = {http://jurnal.unpad.ac.id/biotika,},

doi = {https://doi.org/10.24198/biotika.v18i2.28459},

issn = {2621-4180},

year  = {2020},

date = {2020-12-23},

journal = {BIOTIKA Jurnal Ilmiah Biologi},

volume = {18},

number = {2},

pages = {9-24},

abstract = {Agrowisata merupakan aktivitas wisata yang melibatkan kompleksitas ekosistem agro yang didalamnya tidak terlepas dari keberadaan tumbuhan bawah yang identik dengan gulma maupun tumbuhan hias. Tujuan dari penelitian ini adalah untuk menginventarisasi spesies tumbuhan bawah pada lahan perkebunan ubi cilembu (Ipomoea batatas L.) dan taman pinus (Pinus merkusii Jungh. \& de Vriese) di Kawasan Agrowisata Pangjugjugan, Desa Cilembu, Kabupaten Sumedang. Penelitian dilakukan pada bulan Januari 2020 dengan menggunakan metode survei langsung. Tumbuhan bawah yang dijumpai di lahan perkebunan ubi cilembu dan taman pinus dicatat nama spesies, nama lokal, dan familinya pada lembar pencatatan lalu diidentifikasi. Berdasarkan hasil penelitian, sebanyak 79 spesies yang tersebar pada 30 famili. Asteraceae dan Poaceae merupakan famili tumbuhan dengan jumlah spesies terbanyak yang ditemukan di Kawasan Agrowisata Pangjugjugan, yaitu berturut-turut sebanyak 16 spesies dan 10 spesies.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Tambunan2020,

title = {Jenis-Jenis Tumbuhan Parasit dan Persebarannya di Institut Teknologi Bandung (ITB) Kampus Ganesha},

author = {Meidoraeka Rigine Tambunan and Reza Raihandhany Yus },

url = {https://journal.ipb.ac.id/index.php/sumberdayahayati/article/view/30336},

doi = {https://doi.org/10.29244/jsdh.6.2.47-55},

issn = {2477-037X},

year  = {2020},

date = {2020-11-30},

journal = {Jurnal Sumberdaya HAYATI},

volume = {6},

number = {2},

pages = {47-55},

abstract = {Parasitic plants are a group of plants that live and have a broad ecological distribution which in general attack trees, shrubs or herbs to be used as a host. Some parasitic plants attacked some plants in Institut Teknologi Bandung (ITB) Ganesha Campus, Bandung. Exploration and collection of these parasitic plants in this area are conducted. Three parasitic plants species, such as Cuscuta australis, Scurrula parasitica, and Dendrophthoe pentandra are recorded and they attack 7 other plants species in ITB Ganesha. S. parasitica is reported as the highest population species to parasiting 5 plants species, while C. australis only parasiting 3 plants species and D. pendantra is parasiting 4 plants.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wicaksono2020d,

title = {A Plant within a Plant: Insights on the Development of the Rafflesia Endophyte within its Host},

author = {Adhityo Wicaksono and Sofi Mursidawati and Jeanmaire Molina},

url = {https://link.springer.com/article/10.1007/s12229-020-09236-w#citeas},

doi = {https://doi.org/10.1007/s12229-020-09236-w},

issn = {0006-8101},

year  = {2020},

date = {2020-11-24},

journal = {The Botanical Review },

abstract = {Rafflesia produces the largest single flowers in the world, at the expense of its host vine, Tetrastigma, yet it begins as an inconspicuous endophyte. It is unknown how the Rafflesia seed gets into the host and germinates. Multiple locals claim to have successfully grown the holoparasitic flower from seeds resulting in blooms. Using available morpho-histological studies, combined with descriptions from local Rafflesia seed growers, as well as unpublished details of our own work, we filled in the missing details of Rafflesia’s life cycle from seed germination to endophyte inside the host before it transitions to its flowering stage. Post-germination, the Rafflesia endophyte forms a clonal network of vegetative meristematic cells, separated by the dividing host tissue, each meristematic cell cluster eventually developing into the primordial floral bud or protocorm. We propose future work involving mass spectrometry imaging to characterize the metabolites that allow communication between distant endophytic clusters and floral bud induction without destroying the histology of the sample.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{daSilva2020b,

title = {Cryopreservation of carnation (Dianthus caryophyllus L.) and other Dianthus species},

author = {Jaime A. Teixeira da Silva and Adhityo Wicaksono and Florent Engelmann},

url = {https://link.springer.com/article/10.1007%2Fs00425-020-03510-2},

doi = {https://doi.org/10.1007/s00425-020-03510-2},

issn = { 1432-2048},

year  = {2020},

date = {2020-11-16},

journal = {Planta},

volume = {252},

number = {105},

pages = {1-9},

abstract = {Carnation (Dianthus caryophyllus L.) is an important ornamental plant that is used as a potted plant as well as a cut flower. Important Dianthus germplasm would benefit from long-term strategies such as cryopreservation. Unlike the in vitro tissue culture literature of this ornamental, which has been studied in considerable detail, and with several genetic transformation protocols, surprisingly, the literature on its cryopreservation is still fairly scant, with barely two dozen or so studies, mostly having employed shoot tips. Early (\< 2007) and more recent (2007\textendash2020) cryopreservation techniques for carnation, including ultra-rapid cooling, encapsulation-vitrification, and encapsulation-dehydration, efficiently replaced programmed slow cooling processes used in early studies in the 1980s. Two large gaps (1997\textendash2006, and 2016\textendash2020) in which no carnation cryopreservation studies were published, requires future studies to cover new knowledge to fill gaps in information. Carnation cryopreservation research would benefit from testing a wide range of in vitro explants, new techniques such as the cryo-mesh, improved regeneration protocols for post-cryopreserved material, and the use of low-temperature storage as a mid- to long-term complementary germplasm storage strategy. This mini-review provides details of what has been achieved thus far and future objectives that could fortify cryopreservation research of this ornamental, as well as provide a robust long-term germplasm repository.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wendy2020hb,

title = {Thottea tapanuliensis (Aristolochiaceae):  A new species from Sumatra, Indonesia},

author = {W A Mustaqim and Hirmas F. Putra

},

url = {https://openjournals.library.sydney.edu.au/index.php/TEL/article/viewFile/14535/13128},

doi = {dx.doi.org/10.7751/telopea14535},

issn = {2200-4025 },

year  = {2020},

date = {2020-11-04},

journal = {Telopea Journal of Plant Systematics},

volume = {23},

pages = {163-168},

abstract = {Thottea tapanuliensis Mustaqim (Aristolochiaceae) is described here based on a plant collected from the west coast of northern Sumatra. This species is only known from the type collection and its threat ranking is assessed here as Critically Endangered. Morphological descriptions, photographs, a distribution map, and discussions are provided, as is a key to all Thottea species in Sumatra.

},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mustaqim2020cb,

title = {Melothria (Cucurbitaceae): A new genus record of naturalized cucumber in Sumatra},

author = {Wendy A. Mustaqim and Hirmas F. Putra},

url = {http://www.ptti.or.id/journal/index.php/Floribunda/article/view/318},

doi = {10.32556/floribunda.v6i5.2020.318},

issn = { 2460 - 6944},

year  = {2020},

date = {2020-10-29},

journal = {Floribunda},

volume = {6},

number = {5},

pages = {183-187},

abstract = {The first record of a naturalized cucumber genus Melothria (Cucurbitaceae) is presented for Sumatra, represented by one cosmopolitan species Melothria pendula. The species has been found during an exploration in the northern part of the island. A morphological description, distribution map, brief discussions, and photographs are given.

},

keywords = {},

pubstate = {published},

tppubtype = {article}

}